KJ Hill caught two touchdowns passes as Ohio State turned a 14-point halftime deficit into a 34-21 win.
Trevor Lawrence and No. 3 Clemson will roll into the College Football Playoff riding a 28-game winning streak.
The Bison have now won 34 straight, can extend it next weekend.
Jonathan Taylor has rushed for 135 yards and a touchdown through a 21-7 first half in the Big Ten Championship.
Trevor Lawrence and Tee Higgins have been explosive for Clemson in the first half of the ACC Championship Game.